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What is polymyxin b/trimethoprim-ophthalmic, and how does it work (mechanism of action)?Polymyxin B sulfate/trimethoprim is an antibiotic eye drop composed of two drugs. Polymyxin B sulfate works by altering bacterial cell wall structure that causes the leaking out of cellular contents that can result in cell death. Trimethoprim is an antibiotic that interferes with the production of tetrahydrofolic acid, a chemical that is necessary for bacteria and human cells to produce proteins. Trimethoprim inhibits production of tetrahydrofolic acid by inhibiting the enzyme responsible for making tetrahydrofolic acid from dihydrofolic acid. This inhibition interferes with the ability of bacteria to survive. Polymyxin B sulfate/trimethoprim is effective against gram-positive and gram-negative bacteria such as:
The FDA approved polymyxin B sulphate/trimethoprim in October 1988. What brand names are available for polymyxin b/trimethoprim-ophthalmic?Polytrim Is polymyxin b/trimethoprim-ophthalmic available as a generic drug?Yes Do I need a prescription for polymyxin b/trimethoprim-ophthalmic?Yes What are the side effects of polymyxin b/trimethoprim-ophthalmic?Side effects of polymyxin B sulfate/trimethoprim are
What is the dosage for polymyxin b/trimethoprim-ophthalmic?The recommended dosing for polymyxin B sulfate/trimethoprim is to apply 1 drop into the affected eye(s) every 3 hours for 7 to 10 days with a maximum of 6 doses per day. Which drugs or supplements interact with polymyxin b/trimethoprim-ophthalmic?: Drug interactions have not been established for polymyxin B sulfate/trimethoprim combination eye drops. SLIDESHOWPink Eye (Conjunctivitis) Symptoms, Causes, Treatments See SlideshowIs polymyxin b/trimethoprim-ophthalmic safe to take if I'm pregnant or breastfeeding?
: There are no adequate studies done on polymyxin B sulfate/trimethoprim to determine safe and effective use in pregnant women. It is not known whether polymyxin B sulfate/trimethoprim enters breast milk. It is best use caution before using it in nursing mothers. What else should I know about polymyxin b/trimethoprim-ophthalmic?What preparations of polymyxin b/trimethoprim-ophthalmic are available?Polymyxin B sulfate/trimethoprim is a sterile eye drop, containing polymyxin B sulfate 10,000 units/ml and trimethoprim sulfate 1 mg/ml, available in 10 ml dispenser bottles. How should I keep polymyxin b/trimethoprim-ophthalmic stored?Store polymyxin B sulfate/trimethoprim between temperatures of 15 C to 25 C (59 F - 77 F). Latest Health News
Trending ArticlesSummaryPolymyxin B sulfate and trimethoprim (Polytrim) is an antibacterial eye drop prescribed to treat bacterial conjunctivitis and blepharoconjunctivitis of the eyes. Side effects, drug interactions, pregnancy safety, dosage, and storage information should be reviewed prior to using this medication. Multimedia: Slideshows, Images & Quizzes
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Treatment & DiagnosisMedications & SupplementsQUESTIONWhat causes dry eyes? See AnswerReport Problems to the Food and Drug AdministrationYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. References FDA Prescribing Information. Can polymyxin B treat a stye?If identified early, the use of non–neomycin-containing antibiotic ointment such as gentamicin or polymyxin-B and bacitracin ophthalmic ointment combined with frequent applications of warm moist packs will usually resolve the problem.
Does polymyxin B sulfate and trimethoprim treat pink eye?Polymyxin B and trimethoprim ophthalmic combination is used to treat bacterial infections of the eye including conjunctivitis (pinkeye; infection of the membrane that covers the outside of the eyeball and the inside of the eyelid) or blepharoconjunctivitis (infection of the membrane that covers the outside of the ...
Can you put polymyxin in your eye?How to use Polymyxin B SUL-TRIMETHOPRIM Drops. To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface. Use in the eyes only.
What are the side effects of polymyxin eye drops?Common side effects may include: mild burning, stinging, or itching of your eyes.. eye pain, swelling, redness, or severe discomfort;. crusting or drainage (may be signs of infection);. swelling or redness of your eyelids; or.. new or worsening symptoms.. |