Sample collaborative practice agreement nurse practitioner massachusetts

The final version, 244 CMR 4.00: ADVANCED PRACTICE REGISTERED NURSING, was published and took effect on September 3, 2021.

The regulations can be found at: //www.mass.gov/doc/244-cmr-4-advanced-practice-registered-nursing/download

The major changes for Certified Nurse Practitioners relate to independent prescriptive practice and authority to serve as a Qualified Healthcare Professional to supervise the prescriptive practice of other APRNs.

As outlined in 244 CMR 4.07 (2):
(a) CRNAs, CNPs or PNMHCSs with a minimum of two years of supervised practice may engage in prescriptive practice without supervision upon submission of an attestation to the Board that the CRNA, CNP or PNMHCS has completed a minimum of two years of supervised practice by a Qualified Healthcare Professional.

Per 244 CMR 4.07 (d), a Qualified Healthcare Professional is defined for APRNs as:
2. a CRNA, CNP or PNMHCS who holds:
a. a valid Registered Nurse license in good standing issued by the Board; and
b. advanced practice authorization issued by the Board that it is in the same clinical category as the person being supervised or advanced practice authorization in an area appropriately related to the practice of the person being supervised; and
3. a controlled substance registration issued by the U.S. Drug Enforcement Administration, or the Department of Public Health, or both, for a minimum of one year;
and
4. either:
a. a combination of supervised practice for a minimum of two years plus independent practice authority for a minimum of one year; or
b. three years of independent practice authority.

The MCNP had requested changes in the language related to the definition of Qualified Healthcare Professional, specifically the removal of the 1-year of independent practice authority requirement. Based on the statutory language in the authorizing legislation which required that a minimum number of years of independent practice be specified in the regulations, the Board is not able to change this language/requirement.

The regulations require that a Qualified Healthcare Professional (QHP) who is an APRN have at least one year of independent prescriptive practice. 
The regulations do not require any formal attestations for NPs who serve as QHPs. 

We have sought clarification from the BORN as to whether independent practice under the March 2020 - June 2021 COVID Emergency Order (EO) satisfies this requirement.  We have confirmed that the one year of independent practice may have occurred during the EO time period.

Independent practice eligibility under the emergency order alone however, does not satisfy the requirement. CNPs who would like to claim independent practice during the EO period and start serving as a QHP may need to provide evidence to support their eligibility. This may include, but is not limited to:
1.  Evidence they stopped functioning under prescriptive guidelines; and
2.  Evidence they terminated the supervisory relationship with their collaborating physician (during the period being claimed as independent practice).

The Mass Controlled Substance Registration system has made changes so that APRNs can now formally amend their MCSR to indicate their independent practice status. Once an individual MCSR is updated, the APRN will be listed without an associated supervising physician, and this will serve as an official record of their independent status.

For this reason, we encourage any APRNs who are eager to serve as QHPs and do not have evidence of independent practice under the emergency order to update their MCSR as soon as possible so the 1-year period of independent practice can commence. (See instructions below.)

PLEASE NOTE, if you are employed by a group medical practice or larger healthcare institution, we recommend that you FIRST check with your employer to make sure they have addressed any internal policies or EMR changes that will need to be implemented to support your change to independent practice authority.

The MCNP will be hosting an open Zoom meeting in the coming weeks for members who have questions, and in the meantime feel free to Contact Us.

Thank you to all of our members and volunteers who supported our legislative efforts to pass Full Practice Authority and reach this milestone.

The Massachusetts Coalition of Nurse Practitioners

  • This page, Learn more about prescriptive authority requirements and practice guidelines, is offered by
  • Board of Registration in Nursing
  • Bureau of Health Professions Licensure
  • Department of Public Health

What are prescriptive guidelines?

Guidelines are written instructions and procedures which describe the methods that APRNs, who require supervised prescriptive practice, are to follow when managing medications.  The guidelines specify the instances when referral or consultation with the Qualified Healthcare Professional (QHP) are required for appropriate medication management.

When an APRN registers with DCP as an APRN with supervised prescriptive practice, they are required to sign an attestation that they have a QHP supervising their practice and have developed mutually agreed upon guidelines.

The Board provides an Audit Tool for Compliance with the Regulations at 244 CMR 4.00 and to help with guideline development. 

  • Certified nurse midwives (CNMs) are not required to have guidelines or supervision.
  • Clinical nurse specialists (CNSs) are not authorized by statute to register for prescriptive practice.

Contact the DCP at (617) 973-0800 or  for more information regarding MCSR requirements.  

Additional Resources for

Education requirements for prescribers

To apply for prescriptive authority from MA Controlled Substance Registration (MCSR) and to renew your APRN authorization every two years, all prescribers must complete education relative to:

  • Effective pain management
  • The risks of abuse and addiction associated with opioid medication
  • Identification of patients at risk for substance use disorders
  • Counseling patients about the side effects, addictive nature and proper storage and disposal of prescription medications
  • Appropriate prescription quantities for prescription medications that have an increased risk of abuse
  • Opioid antagonists, overdose prevention treatments and instances in which a patient may be advised on both the use of and ways to access opioid antagonists and overdose prevention treatments.

These requirements are in accordance to Massachusetts state law M.G.L. c. 94C s.18(e). Please note that M.G.L. c. 94C s.18(e) does not specify a minimum number of contact hours to comply with this education requirement.

Nurse prescribers may choose any program that meets the required content and is consistent with the Board’s continuing education requirements, such as the free course work at SCOPE of Pain or National Institute on Drug Abuse (NIDA).

Prescriptive guidelines for practicing in more than one setting

  • When an APRN registers with the Department of Public Health Drug Control Program (DCP) for prescriptive practice as an APRN with independent prescriptive practice authority, and they are responsible for ordering or storing controlled substances, they need a MA Controlled Substance Registration (MCSR) at each site address. Please refer to the DCP requirements in 105 CMR 700.00 and 105 CMR 721.

Contact the DCP at (617) 973-0800 or  for more information regarding MCSR requirements.

Requirement to register for and use the Prescription Monitoring Program (PMP)

The PMP uses a computer-based, Electronic Data Transfer (EDT) system to collect prescription data from Massachusetts community hospitals, outpatient and clinic pharmacies, and out-of-state mail order pharmacies that deliver to patients in Massachusetts. PMP is a tool that supports safe prescribing and dispensing and assists in addressing prescription drug misuse and abuse.

You must register for and use Massachusetts Prescription Awareness Tool (MassPAT) online.

Do nurse practitioners need a collaborative agreement in Massachusetts?

Massachusetts Nurse Practitioner Supervision Laws This means that to practice to their full potential, nurse practitioners in Massachusetts must have a collaborative practice agreement with a physician. The physician does not need to be on-site but must be available for consultation with the NP in person or by phone.

How do you write a collaborative practice agreement?

According to the CDC, a collaborative practice agreement should include these parts:.
Explanation of the purpose of the agreement..
A list of the parties to the agreement..
The patients who are included in the agreement (either a specific list of patients or a group of patients).
Care functions authorized by the agreement..

Can nurse practitioners practice independently in Massachusetts?

Massachusetts is the 23rd state to allow NPs to practice independently. Although NPs have advanced training, many states still require they have a supervision agreement with a physician.

What is a collaborative agreement for nurse practitioners?

A collaborative practice agreement is a written contract that establishes a working relationship between the nurse practitioner and the physician. Often this means that the physician will provide supervision and guidance, and be available for consultations with the NP.

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